STEP 1: It could be an add-on causing the issue.
Start>Control Panel>Internet Options>Advanced tab, uncheck "enable third-party browser extensions"
close all open IE windows and restart IE for the full changes to take effect…
STEP 2: started after the Windows 10 update
Does this in both IE 11, and Edge. Attempting to access a bank account. Have tried all the normal fixes, Uncheck the Allow 3rd Party box under Advanced, reset the trusted sites list and permissions to allow everything. I was going to attempt a reinstall, but I can't find a uninstaller under any remove programs application. This computer is also not joined to a AD, I have also checked the user profile to make sure it was assigned to the Admin group for Local Policies.
STEP 3: Enable Flash in Chrome
Chrome might have displayed the ‘This plug-in is not supported’ error message because Flash is currently not enabled on the Chrome app, which explains why the affected webpage was not allowed to use Flash to run its content. In that case, all you have to do to make things right is enable Flash.
STEP 4: Install the latest flah player; Update Flash
Here, we are assuming the error notification came up because the Flash player is yet to be installed on the Chrome browser on your PC. Well, this explains the affected site’s struggles with the media content. If the required plugin is nonexistent, the content cannot be loaded or played.
STEP 5: Clear the browsing data in Chrome
Here, we are considering the possibility where Flash issues have something to do with corrupted data being used by your browser. If the assumptions (made here) hold true, then you will be able to fix the ‘This plug-in is not supported’ error by clearing Chrome browsing data. When you force Chrome to clear its browsing data, the application gets rid of bad files, entries, and packages that define your experience on the web.
STEP 6: Use another browser to test things (preferably Internet Explorer)
Since you are yet to resolve the problem, it is time you considered the possibility where the problem is down to Chrome’s lack of support for a different plugin (and not Flash). The site on you which you encountered the ‘This plug-in is not supported’ error might have displayed the notification to inform you that your browser cannot play its media content because it is not running the Java plugin, for example.
STEP 7: Use the IE tab extension in Chrome
If you somehow managed to find out that the plugin error is down to Chrome’s lack of support for the needed plugins on its platform – especially after you saw the media content on the affected webpage play normally on Internet Explorer – then you can make an addition to Chrome setup to fix things. Here, we want you to add or install a special extension (IE tab extension) that simulates the Internet Explorer environment in Chrome.
STEP 8: Use the NoPlugin Extension
NoPlugin is an incredibly useful extension through which browsers get to play multimedia content even when support for the plugins (needed to play the content) is lacking on their platforms. In other words, the extension enhances browsers’ compatibility with old websites (that still use outdated plugin technologies like Flash). NoPlugin works by converting the plugin code to HTML5 and then renders the result so that the media content plays right in the browser.
STEP 9: Update Chrome
Finally, we have to consider the possibility where the plugin is not supported issue is not down to Chrome’s lack of support for old plugins but rather newer technologies. Perhaps, the affected website or webpage is using some HTML5 technologies that your current browser build does not recognize. In that case, we can safely infer that your computer is running an old or outdated version of Chrome – because the newest Chrome build is always embedded with support for the relevant web technologies.